Salt Chemistry
Phenibut Free Base vs. Hydrochloride Salt
Phenibut is commonly supplied as the hydrochloride salt. The salt and the free base are distinct materials with different identifiers and properties.
- Free baseC10H13NO2, MW 179.22 g/mol, CAS 1078-21-3
- HydrochlorideC10H14ClNO2, MW 215.68 g/mol, CAS 3060-41-1
Why the salt form is common
Converting an amino acid to its hydrochloride salt generally produces a crystalline solid that is convenient to handle and typically more water-soluble than the free base. This is a physicochemical/handling consideration relevant to laboratory work, not a statement about use.
Documentation implication
Because they are different substances, always document the exact form. A Certificate of Analysis or Safety Data Sheet applies to the specific form and lot. See physical & chemical properties and identifiers.
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